What is CBD?
Cannabidiol (CBD) is one of many powerful compounds (cannabinoids) found in the cannabis sativa plant and is non-psychotropic. CBD is being explored by scientists for patients looking for relief from inflammation, pain, anxiety, psychosis, seizures, spasms, and other conditions .
Scientific and clinical research is uncovering CBD’s potential as a treatment for a wide range of conditions, including arthritis, diabetes, alcoholism, MS, chronic pain, schizophrenia, PTSD, depression, antibiotic-resistant infections, epilepsy, and other neurological disorders. CBD has demonstrable neuroprotective and neurogenic effects, and its anti-cancer properties are currently being investigated in the United States and around the world. See United States Patent #6,630,507 . Oils that contain concentrations of CBD are known as CBD oils. The concentration and uses of different oils vary.
What is the Endocannabinoid System (ECS)?
The endocannabinoid system (ECS) is a biological system which plays many important roles in the human body. Scientists first discovered the system while trying to understand the effects of cannabis, and named it the endocannabinoid system for this reason. Israeli Scientist, Dr. Raphael Mechoulam, and his research team played a key role in both the discoveries of THC and the ECS, as seen in the wonderful documentary film, “The Scientist“. Endo stands for endogenous, which means originating within the body. Cannabinoid refers to the group of compounds that activate this system. It is perhaps the most important physiologic system involved in establishing and maintaining human health.
Endocannabinoids and their receptors are found throughout the body: in the brain, organs, connective tissues, glands, and immune cells. In each tissue, the cannabinoid system performs different tasks, but the goal is always the same: homeostasis, the maintenance of a stable internal environment despite fluctuations in the external environment. Cannabinoids promote homeostasis at every level of biological life. The ECS can be found in all tetrapod vertebrates including, amphibians, reptiles, birds and mammals.
The ECS is a major target of medical research worldwide because of its widespread effects and therapeutic potential to heal a wide variety of seemingly unrelated conditions. New studies are discovering what this amazing network does inside our bodies and so much more remains to be uncovered.
The role of the endocannabinoid system in the regulation of endocrine function and in the control of energy balance in humans.
Introduction to the Endocannabinoid System
What are Cannabinoid Receptors (CB1 & CB2)?
Cannabinoid receptors are part of the endocannabinoid system (ECS), are found all throughout the body, and play a host of vital roles in our bodies. They are composed of two types of receptors, referred to as CB1 and CB2. Certain receptors are more concentrated in specific regions. CB1 receptors are abundant in the central nervous system. CB2 receptors are more often found on immune cells, in the gastrointestinal tract, and in the peripheral nervous system. The diversity of receptor locations shows the wide variety of functions in which they are involved and the direct impact they have on our ECS for day-to-day bodily function, including appetite, pain-sensation, mood, memory and more.
Why Are Cannabinoid Receptors Important?
Cannabinoid receptors 1 and 2 (CB1 and CB2), their distribution, ligands and functional involvement in nervous system structures–a short review
What is the difference between Industrial Hemp and Marijuana?
The Industrial Hemp and Marijuana plant are the same plant species, cannabis sativa. Hemp has a more fibrous stalk and grows taller than marijuana, has significantly lower amounts of tetrahydrocannabinol (THC), (less than 0.3%), and has been cultivated for thousands of years for a variety of uses including paper, rope, textiles, clothing, biodegradable plastics, paint, insulation, biofuel, food, animal feed and organic body care. Hemp seed is a great source of protein and essential fatty acids, contains high amounts of vitamin E, phosphorus, potassium, sodium, magnesium, sulfur, calcium, iron and zinc. Both cannabis varieties are cultivated for their cannabidiols (CBD Oil), terpenes and other medicinal uses.
What is the difference between CBD from Hemp vs. CBD from Marijuana ?
CBD from the hemp plant is molecularly the same exact CBD as the CBD from the medical marijuana plant. The amount of CBD found in each cannabis strain varies.
What is the difference between “FULL SPECTRUM” hemp/CBD OIL and CBD ISOLATE?
Full spectrum CBD contains all of the cannabinoids and terpenes in the marijuana or hemp plant from which it was sourced. CBD isolate has been extracted and reduced down to the CBD molecule. Isolate does not have other inherent benefits that come from the natural cannabinoids and terpenes found in the whole plant. Scientific research is showing that better results are achieved when CBD is combined with other natural properties from the plant (a whole plant extract) and create what has become known as the “entourage effect”.
What is the "Entourage Effect"?
Whole plant extractions of cannabis contain CBD, THC and hundreds of other trace compounds including terpenes and other cannabinoids. Scientists call the interactive synergy of the compounds “the entourage effect”. This “entourage effect” magnifies the therapeutic benefits of the plant’s individual components. The entourage effect is the belief that medicinal impact of the compounds in cannabis work better together than if the compounds are isolated.
What is "raw" CBD oil?
Raw cannabis is the fresh flower and leaves trimmed directly from the plant and can be used in salads, or ‘juiced’ in smoothies and juices like other nutrient-rich leafy greens. Raw CBD oil contains CBD-A, the ‘raw’, unheated and uncured cannabinoid. Raw CBD has a higher concentration of plant material and other cannabinoids, terpenes and phenols, including CBC, CBN, CBV and CBG. Since no heating of the cannabis is involved with the extraction process, other enzymes and vitamins that are sensitive to heat remain available. Pure raw hemp CBD oil has a strong, earthy taste.
What is Rick Simpson Oil or 'RSO'?
Rick Simpson is a medical marijuana activist who has been providing people with information about the healing powers of cannabis oil since 2003. He has reported treating patients with all types of conditions. “Rick Simpson Oil,” commonly referred to as RSO, refers to an extremely potent decarboxylated extract produced from strong indica strains of the cannabis plant. RSO is unique in the technique he uses, reducing the plant matter in a solvent solution (e.g. alcohol), and concentrating the cannabinoids to make the oil. Rick Simpson oil is said to cure or control many ailments and medical issues.
How much CBD should I take?
The correct dose of CBD varies significantly from individual to individual. The optimal dose will also depend on the condition being treated and method of delivery of CBD being used.
CBD can be delivered into your body in a number of different ways: including smoking/vaping, edibles, capsules, tinctures, topicals and more.
The easiest, and most effective, is using CBD oil, or tinctures which are administered under the tongue and absorbed directly into the bloodstream. Effective dosages range from as little as a few milligrams of CBD oil to 1000mg+ or more.
Factors that may affect your dosage include your weight, metabolism, diet, sensitivity to CBD, the illness or ailment for which you are using CBD and the quality and potency of the CBD oil you choose.
Start small and always check the manufacturer’s suggestions. Use the same dose/ratio/strength for several days. If you feel any discomfort from a dosage, decrease the amount you use the next time you take CBD. Gradually increase as needed, scaling up just a few milligrams at a time.
Record and observe the effects to become familiar with how your body responds to CBD before changing/increasing the dose. Take your CBD at the same time each day.
Keep a notebook or spreadsheet and record:
- Type/form of CBD
- Dosage and strength
- Time of day CBD is taken
- Foods and times you eat
- How you felt before, after and at different times throughout the day.
These are merely suggestions and should not be construed as medical advice. Always check with your physician or trained medical professional before starting a new medication and how it may affect you and possible drug interactions with anything you are currently taking. This information should not be considered medical advice. Consult your doctor if you have a history of alcohol or drug abuse, mental illness, or are pregnant or breastfeeding.
Will I fail a drug test if I use CBD?
Many CBD products are made with Full Spectrum CBD which may contain trace amounts of naturally occurring THC that are below the Federal Legal Limit (less than 0.3% THC). In most cases CBD products will not be detectable on a urine or saliva test, but if you are consuming large doses of ‘Full Spectrum’ CBD, THC may register on a drug test.
Research the products carefully. Look on the company or product website and assess the credibility and transparency of the company. Make sure you see analytical test results of the same product and batch number you are consuming. It’s important to be confident in the company supplying your CBD products by knowing the potency and safety of the ingredients and products.
If your job requires testing for THC, we recommend that you check with your employer and doctor before taking any CBD products.
Will taking CBD effect or react with other medications I am using?
It is always imperative that you check with your physician about potential drug interactions before starting any new medication. CBD is a safe substance with minimal side effects, but research is ongoing and it may not be known if CBD has any interaction with certain medications you may be taking. If you are starting a CBD-rich treatment regimen, you should monitor changes in your blood levels of prescription medications and, if need be, adjust dosage. Always check with your physician.
What are the side effects of CBD?
CBD is a safe substance with minimal side effects, however, everyone’s unique endocannabinoid system may respond differently to CBD. CBD may affect you differently than others and may also have a different effect if you are taking other medications. If you are starting a CBD regimen, you should consult with your physician.
Is a medical card needed to purchase CBD products?
In states where it has been approved, any products (including CBD) derived from the medical marijuana cannabis plant are considered controlled substances, and a Medical Marijuana Card is needed for purchase. CBD products derived from the cannabis hemp plant do not require a medical marijuana card to purchase.
What is “CBD-rich” vs. “CBD dominant?
The term “CBD-rich,” refers to a cannabis strain or product that has equal amounts of CBD and THC, or has more CBD than THC. The term “CBD-dominant,” refers to strains or products that are CBD-rich but have very little THC content.
Is CBD Kosher?
The question has many angles to be considered. The simplest answer is that when cannabis is used as a medical treatment, it does not need to be certified. However, infused edible cannabis products must be declared Kosher, like any other products ingested by observant Jews. For a more information, read, ‘A HIGHER AUTHORITY: THE RABBINICAL ANSWER TO MEDICAL MARIJUANA’ from The Jerusalem Post’s Health & Science Section.
How long does it take for CBD to work or to take effect?
Everyone has a unique endocannabinoid system. Which method you choose for administration will affect the time of onset and duration of the effects. What works best for you may be different than for others.
Since CBD does not produce a ‘high’, the effects are often subtle and overlooked when first using CBD. Most people are not sure what to expect and do not realize that it is beginning to help their condition and that pain they may have had is no longer there or not as intense. It is often described as a ‘subtle calming’ or a ‘weight off the shoulders’. After several uses, you will notice it “taking the edge” off and feeling a sense of ‘calm’.
Inhalation has the fasted onset and is a good delivery method for treating symptoms that require immediate relief. For oral delivery, tinctures are immediately absorbed through the mucous membrane under the tongue and have a faster onset than capsules and soft gels that have to pass through the digestive system.
What CBD products do you recommend?
People use CBD oil for a variety of purposes. In compliance with the US FDA regulations, we are not allowed to make direct health claims in regards to CBD products. Research indicates that CBD could have applications in quite a variety of health ailments and conditions. We encourage you to do your own research before you try any CBD product.
What are the best ways to use CBD?
Finding what works best for you is a matter of personal choice, and it may take trying a few different products and/or delivery systems to find one that compliments your health and lifestyle needs. Overall, CBD products are primarily taken sublingually, ingested, smoked or applied topically.
- Sublingual CBD products are taken orally as sublingual tinctures or sprays, lozenges and gum.
- CBD ingestible products are gelcaps, capsules, edible products including chocolates, gummies, infused cooking oils, baked goods, teas and other beverages.
- CBD can be applied directly to the skin topically as a cream, salve, massage oil, lotion and is also available in transdermal patches.
- CBD can be inhaled, smoked or vaporized with a vape pen.
The best method will depend on your symptoms and/or ailments and personal preference. Inhalation has the fasted onset and is a good delivery method for treating symptoms that require immediate relief. The onset of the effect is slower when taken orally, but effects can last longer in your system. Everyone’s endocannabinoid system is unique, what works for you may be different than for others. See Glossary of Terms for more definitions.